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    Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗體

    • 更新時間:  2023-07-24
    • 產(chǎn)品型號:  eBiosience12-4801-82
    • 簡單描述
    • Host
      Rat
      Isotype
      IgG2a, kappa
      Reactivity
      Mouse
      Conjugate
      PE
      Laser
      Blue Laser, Green Laser, Yellow-Green Laser
      Emit
      575 nm
      Excite
      488 - 561 nm
      Reported Applications
      Flow Cytometric Analysis
    詳細(xì)介紹

    Also known as: Pan Macrophage Marker

    Clone: BM8

    Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo

    Host Rat
    Isotype IgG2a, kappa
    Reactivity Mouse
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Emit 575 nm
    Excite 488 - 561 nm
    Reported Applications Flow Cytometric Analysis

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